Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP26155.15,10-methylene tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)    
Predicted Functional Partners:
fgd
Glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria.
  
   
 0.776
AMP23363.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.758
AMP25351.1
Deazaflavin-dependent nitroreductase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.756
AMP25923.1
Deazaflavin-dependent nitroreductase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.746
AMP23762.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.746
AMP25518.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.746
AMP22507.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.745
AMP23535.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.728
AMP22593.1
Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.727
AMP26156.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.725
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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