Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AMP24009.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)    
Predicted Functional Partners:
AMP24010.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.975
AMP24007.1
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.686
AMP24258.1
acyl-ACP thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.682
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.662
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
  
    0.659
AMP24008.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.620
AMP26206.1
Beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.601
AMP23637.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.576
AMP25918.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
AMP26248.1
Heparin-binding hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.545
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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