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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP24132.1Trypsin; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.741
AMP21731.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
  
 
  0.696
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.652
AMP26043.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.651
AMP22947.1
Aminobenzoate oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.592
AMP24822.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.581
AMP26233.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.566
AMP26298.1
Pentapeptide repeat family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.566
AMP26229.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.561
AMP24205.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.519
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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