Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
AMP24283.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)    
Predicted Functional Partners:
AMP24284.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.945
AMP24281.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.856
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
       0.809
AMP24282.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.779
AMP24286.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.714
AMP24280.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.596
AMP25012.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.555
AMP24942.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.544
AMP25446.1
Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.524
mca
GlcNAc-PI de-N-acetylase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
 
     0.502
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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