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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP24516.1Cholesterol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)    
Predicted Functional Partners:
AMP22721.1
Steroid delta-isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.960
AMP26200.1
Steroid C27-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
     
 0.900
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.828
AMP21882.1
Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
     
 0.760
AMP23337.1
Cytochrome P450; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
     
 0.760
AMP25790.1
Steroid C27-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
     
 0.751
AMP23360.1
Steroid C27-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
     
 0.751
AMP26295.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.744
AMP22063.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.731
AMP23192.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.727
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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