Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
manBPhosphomannomutase; Converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)    
Predicted Functional Partners:
AMP24643.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.994
AMP24637.1
GDP-mannose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.954
AMP24642.1
TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.921
AMP22916.1
UDP-glucose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.833
AMP22518.1
Glycogen phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.719
AMP26311.1
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.694
AMP24838.1
Phosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.691
AMP24640.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.654
AMP26455.1
ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.633
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
  
 
 0.619
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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