Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
AMP24642.1TobH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)    
Predicted Functional Partners:
manB
Phosphomannomutase; Converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.921
AMP24643.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.909
cobN
Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.881
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
   
  
 0.879
AMP24528.1
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.877
AMP23700.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.800
AMP26291.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.757
AMP24336.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.750
AMP24972.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.749
AMP25218.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.747
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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