STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP24684.1Isochorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.981
AMP25922.1
Enterobactin synthase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.980
AMP23715.1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.961
AMP24685.1
Acid phosphatase; Forms a homodimer in Mycobacterium tuberculosis; belongs to the dPGM superfamily; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.938
AMP22294.1
Salicylate synthase MbtI; Catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.936
AMP22286.1
Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.934
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.934
AMP24998.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.899
trpC
Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family.
   
 0.891
AMP22942.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.884
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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