Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP24907.1Sulfoacetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)    
Predicted Functional Partners:
AMP24896.1
Sulfoacetaldehyde acetyltransferase; Catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family.
 
 
  0.949
AMP24900.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.939
AMP21786.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.934
AMP26374.1
succinate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.846
sucD-2
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
 
 0.799
AMP24906.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.783
AMP21928.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.697
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.641
aspA
Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.553
AMP25774.1
Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.547
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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