| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMP22256.1 | AMP22742.1 | VC42_05290 | VC42_08305 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| AMP22256.1 | AMP24229.1 | VC42_05290 | VC42_17720 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.899 |
| AMP22256.1 | AMP24914.1 | VC42_05290 | VC42_22135 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.931 |
| AMP22256.1 | glyA | VC42_05290 | VC42_08225 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.946 |
| AMP22256.1 | ilvA | VC42_05290 | VC42_26035 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.905 |
| AMP22256.1 | metXA | VC42_05290 | VC42_19700 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.603 |
| AMP22256.1 | serC | VC42_05290 | VC42_10190 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.471 |
| AMP22256.1 | trpA | VC42_05290 | VC42_26260 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.903 |
| AMP22256.1 | trpB-2 | VC42_05290 | VC42_26255 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.903 |
| AMP22742.1 | AMP22256.1 | VC42_08305 | VC42_05290 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| AMP22742.1 | AMP24229.1 | VC42_08305 | VC42_17720 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.898 |
| AMP22742.1 | AMP24914.1 | VC42_08305 | VC42_22135 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.941 |
| AMP22742.1 | glyA | VC42_08305 | VC42_08225 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
| AMP22742.1 | guaA | VC42_08305 | VC42_19530 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.944 |
| AMP22742.1 | ilvA | VC42_08305 | VC42_26035 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.929 |
| AMP22742.1 | metXA | VC42_08305 | VC42_19700 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.914 |
| AMP22742.1 | serC | VC42_08305 | VC42_10190 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.770 |
| AMP22742.1 | trpA | VC42_08305 | VC42_26260 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.916 |
| AMP22742.1 | trpB-2 | VC42_08305 | VC42_26255 | Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.906 |
| AMP24229.1 | AMP22256.1 | VC42_17720 | VC42_05290 | CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.899 |