STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP24942.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)    
Predicted Functional Partners:
AMP21984.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.940
AMP22048.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.881
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.840
AMP26385.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.801
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.779
AMP22742.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.752
AMP22118.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.714
AMP25087.1
GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.693
AMP24016.1
Lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.692
AMP22741.1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.677
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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