STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMP24981.1Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)    
Predicted Functional Partners:
AMP24982.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.763
AMP24980.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.762
AMP24983.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.761
AMP24984.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
       0.756
AMP24985.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.748
dkgA
2,5-diketo-D-gluconic acid reductase; Methylglyoxal reductase/beta-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.725
AMP25430.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.633
AMP22651.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.628
AMP24044.1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.610
nuoI
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
    
   0.600
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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