STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP25055.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)    
Predicted Functional Partners:
AMP24273.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
AMP26401.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.525
AMP23231.1
Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.524
AMP22589.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.496
AMP22105.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.439
AMP25456.1
butyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
AMP24069.1
butyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.413
AMP25755.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.409
rskA
Anti-sigma K factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regu [...]
  
     0.405
AMP23627.1
DinB family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.401
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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