STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase expression protein HupH; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (111 aa)    
Predicted Functional Partners:
AMP25107.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.960
AMP21530.1
Cytochrome-c3 hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.951
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 
 0.946
AMP22565.1
Formate hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
AMP25101.1
Hydantoin utilization protein C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.888
AMP25096.1
Hydrogenase formation protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.842
AMP25100.1
Hydrogenase maturation protein HypF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.832
AMP26408.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.825
AMP21515.1
Hydrogenase assembly protein HypC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.820
AMP25966.1
Sodium:proton antiporter; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.815
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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