node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMP22164.1 | AMP24448.1 | VC42_04575 | VC42_19075 | Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.737 |
AMP22164.1 | AMP24954.1 | VC42_04575 | VC42_22400 | Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.911 |
AMP22164.1 | AMP26411.1 | VC42_04575 | VC42_23475 | Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. | oxalyl-CoA decarboxylase; Catalyzes the formation of formyl-CoA from oxalyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.832 |
AMP24448.1 | AMP22164.1 | VC42_19075 | VC42_04575 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. | 0.737 |
AMP24448.1 | AMP24954.1 | VC42_19075 | VC42_22400 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
AMP24448.1 | AMP26411.1 | VC42_19075 | VC42_23475 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | oxalyl-CoA decarboxylase; Catalyzes the formation of formyl-CoA from oxalyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.873 |
AMP24448.1 | ilvA | VC42_19075 | VC42_26035 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.950 |
AMP24448.1 | ilvC | VC42_19075 | VC42_22405 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.984 |
AMP24448.1 | leuA | VC42_19075 | VC42_13120 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.926 |
AMP24448.1 | leuB | VC42_19075 | VC42_22425 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.944 |
AMP24954.1 | AMP22164.1 | VC42_22400 | VC42_04575 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. | 0.911 |
AMP24954.1 | AMP24448.1 | VC42_22400 | VC42_19075 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
AMP24954.1 | AMP26411.1 | VC42_22400 | VC42_23475 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | oxalyl-CoA decarboxylase; Catalyzes the formation of formyl-CoA from oxalyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.983 |
AMP24954.1 | ilvA | VC42_22400 | VC42_26035 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.994 |
AMP24954.1 | ilvC | VC42_22400 | VC42_22405 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
AMP24954.1 | leuA | VC42_22400 | VC42_13120 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.983 |
AMP24954.1 | leuB | VC42_22400 | VC42_22425 | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.992 |
AMP26190.1 | AMP26411.1 | VC42_15765 | VC42_23475 | acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. | oxalyl-CoA decarboxylase; Catalyzes the formation of formyl-CoA from oxalyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.891 |
AMP26411.1 | AMP22164.1 | VC42_23475 | VC42_04575 | oxalyl-CoA decarboxylase; Catalyzes the formation of formyl-CoA from oxalyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Alpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. | 0.832 |
AMP26411.1 | AMP24448.1 | VC42_23475 | VC42_19075 | oxalyl-CoA decarboxylase; Catalyzes the formation of formyl-CoA from oxalyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |