STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP26414.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)    
Predicted Functional Partners:
AMP25147.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.680
AMP26415.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.546
AMP25148.1
4'-phosphopantetheinyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the P-Pant transferase superfamily.
       0.541
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.540
nnrE
Membrane protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers [...]
   
    0.474
AMP21549.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.433
AMP22627.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.416
AMP22624.1
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.407
AMP24794.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.400
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
Server load: medium (46%) [HD]