Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMP25577.1Nuclease PIN; Derived by automated computational analysis using gene prediction method: Protein Homology. (677 aa)    
Predicted Functional Partners:
AMP23720.1
Potassium ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.841
AMP21653.1
Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.719
AMP22803.1
Chain-length determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.580
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.566
AMP23721.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.563
AMP26494.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.557
AMP23722.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.510
AMP26495.1
Major facilitator transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.510
AMP24197.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
0.502
AMP21544.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.486
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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