STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP25577.1Nuclease PIN; Derived by automated computational analysis using gene prediction method: Protein Homology. (677 aa)    
Predicted Functional Partners:
AMP23720.1
Potassium ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.908
AMP21544.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.828
AMP23491.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.826
AMP21653.1
Peptide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.808
AMP22803.1
Chain-length determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.664
AMP26494.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.660
AMP23721.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.649
AMP23722.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.638
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.566
AMP21769.1
Riboflavin biosynthesis protein RibA; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the DHBP synthase family.
  
 
 0.558
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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