Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
AMP26522.1Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)    
Predicted Functional Partners:
AMP22512.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.908
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.889
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
  
 0.859
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
  
 0.859
pup
Ubiquitin; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
   
 
 0.809
AMP22621.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.772
AMP22922.1
Peptidase S1; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.772
AMP23297.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.772
AMP23460.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.772
AMP23920.1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.772
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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