STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMP25690.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)    
Predicted Functional Partners:
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.778
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.757
AMP21984.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.740
AMP24914.1
Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.724
AMP25691.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.554
AMP25688.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.516
AMP25689.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.516
AMP22741.1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.507
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.507
AMP25692.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.436
Your Current Organism:
Mycobacterium simiae
NCBI taxonomy Id: 1784
Other names: ATCC 25275, CCUG 29114, CCUG 42427, CIP 104531, DSM 44165, JCM 12377, M. simiae, Mycobacterium habana
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