| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acnA | aspA | AWC28_08910 | AWC28_04835 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.887 |
| acnA | echA1_4 | AWC28_08910 | AWC28_01995 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.615 |
| acnA | fadB | AWC28_08910 | AWC28_06895 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.799 |
| acnA | gabD1_1 | AWC28_08910 | AWC28_02015 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. | 0.619 |
| acnA | gdhA | AWC28_08910 | AWC28_05360 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.659 |
| acnA | kgd | AWC28_08910 | AWC28_17845 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| acnA | ltp1_1_3 | AWC28_08910 | AWC28_01985 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. | 0.616 |
| acnA | mdh | AWC28_08910 | AWC28_17875 | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.861 |
| aspA | acnA | AWC28_04835 | AWC28_08910 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.887 |
| aspA | echA1_4 | AWC28_04835 | AWC28_01995 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.517 |
| aspA | fadB | AWC28_04835 | AWC28_06895 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
| aspA | gabD1_1 | AWC28_04835 | AWC28_02015 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. | 0.647 |
| aspA | gdhA | AWC28_04835 | AWC28_05360 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.527 |
| aspA | kgd | AWC28_04835 | AWC28_17845 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.956 |
| aspA | ltp1_1_3 | AWC28_04835 | AWC28_01985 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family. | 0.497 |
| aspA | mdh | AWC28_04835 | AWC28_17875 | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.995 |
| echA1_4 | acnA | AWC28_01995 | AWC28_08910 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.615 |
| echA1_4 | aspA | AWC28_01995 | AWC28_04835 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Class II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.517 |
| echA1_4 | fadB | AWC28_01995 | AWC28_06895 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.609 |
| echA1_4 | flhA_1 | AWC28_01995 | AWC28_02010 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.485 |