Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
kstD3-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)    
Predicted Functional Partners:
kshA_3
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.989
hmp_2
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.971
ORW90963.1
Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.959
ksi_2
Ketosteroid isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.952
ORW95636.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.943
kshA_2
(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.933
ORW90635.1
3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.932
ORW97517.1
23S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.932
kshA_1
2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.931
ksi_1
Steroid delta-isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.927
Your Current Organism:
Mycolicibacter terrae
NCBI taxonomy Id: 1788
Other names: ATCC 15755, CCUG 27847, CIP 104321, DSM 43227, JCM 12143, LMG 10394, LMG:10394, M. terrae, Mycobacterium terrae
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