Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORW94590.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.716
hbhA
Heparin-binding hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.701
ORW88633.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.700
ORW93595.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.659
espR
Secretion protein EspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.637
ORW88528.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.609
ORW97479.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.597
cspA
Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.580
ORW94106.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.578
ORW97594.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.552
Your Current Organism:
Mycolicibacter terrae
NCBI taxonomy Id: 1788
Other names: ATCC 15755, CCUG 27847, CIP 104321, DSM 43227, JCM 12143, LMG 10394, LMG:10394, M. terrae, Mycobacterium terrae
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.