Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cbiX_1Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)    
Predicted Functional Partners:
cysG
Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.994
ORW93507.1
Bifunctional uroporphyrinogen-III synthetase/response regulator domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.943
ORW93756.1
Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; Catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.873
nirA_2
Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.768
narK3
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.764
narK3_2
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.705
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.695
hemD
Bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.655
nirD
Nitrite reductase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.632
nirB
Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.582
Your Current Organism:
Mycolicibacter terrae
NCBI taxonomy Id: 1788
Other names: ATCC 15755, CCUG 27847, CIP 104321, DSM 43227, JCM 12143, LMG 10394, LMG:10394, M. terrae, Mycobacterium terrae
Server load: medium (50%) [HD]