STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORX18652.1methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (514 aa)    
Predicted Functional Partners:
LeuS
leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
gltX
glutamate--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.986
IleS
isoleucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.982
argS
arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.978
ORX20537.1
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
  
 0.975
ORX18653.1
DNAase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.971
lysS
lysine--tRNA ligase; Catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.935
LysS1
lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.930
MetH
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.925
Fmt
methionyl-tRNA formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.922
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.