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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RecNDNA repair protein RecN; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)    
Predicted Functional Partners:
ppnK
NAD(+) kinase; Catalyzes the phosphorylation of NAD to NADP; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.973
ORX21329.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.940
ORX21331.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.940
ppnK-2
16S/23S rRNA (cytidine-2'-O)-methyltransferase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
 0.898
RecA
Recombinase RecA; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.897
pdxp
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.870
UvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
  
 0.839
lexA
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.832
UvrA
ABC-ATPase UvrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.798
RuvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
  
 0.760
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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