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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IspH14-hydroxy-3-methylbut-2-enyl diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)    
Predicted Functional Partners:
IspG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
 
   
 0.951
idsA2_1
Geranylgeranyl pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.944
IspF
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.942
Dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.942
idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
    
 0.941
Idi
Isopentenyl-diphosphate delta-isomerase; Catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.941
idsA
Polyprenyl synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.941
IspE
4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.933
rpsA
30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.918
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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