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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligBATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)    
Predicted Functional Partners:
ligA
DNA ligase (NAD(+)) LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.979
PolA
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.867
LppK
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.839
DnaN
DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.839
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.824
recC
Exodeoxyribonuclease V subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.818
ORX16831.1
5'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.791
CstA
Phosphoesterase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.786
DinB
DNA polymerase IV; Involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.755
ORX13529.1
DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.737
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.