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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORX18247.1Plasmid replication initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)    
Predicted Functional Partners:
ORX18246.1
Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.944
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
  
 0.917
ORX15868.1
Fatty acyl-AMP ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.908
AWC32_11580
Transcriptional regulator; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.899
ORX20040.1
Type VII secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.852
ORX19608.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.852
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.852
ORX21974.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.852
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
 
 0.827
rplQ
50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.787
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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