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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORX15855.1Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)    
Predicted Functional Partners:
ORX16824.1
Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.924
ORX21644.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
  0.900
ORX15854.1
LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.832
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.713
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.616
ORX17122.1
Prolyl oligopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.513
GcvP
Glycine dehydrogenase (aminomethyl-transferring); Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.433
otsB
Trehalose phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
  
    0.427
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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