Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (348 aa)    
Predicted Functional Partners:
ORX21415.1
Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
ORX21416.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
HemE
Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family.
 
  
 0.972
ORX20533.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.947
ORX21538.1
Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.933
MmcO
Oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.928
bfr
Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
     
 0.915
CtaB_1
Protoheme IX farnesyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.913
CtaB_2
Protoheme IX farnesyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.913
BfrB_1
Bacterioferritin; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.909
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
Server load: medium (46%) [HD]