Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ORX21961.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (314 aa)    
Predicted Functional Partners:
ORX21960.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     0.964
ORX18251.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.950
Cya
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.940
ORX12232.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.935
ORX19775.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.925
ORX21235.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.922
ORX22112.1
Adenylyl cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.919
ORX21761.1
Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.907
RelA
GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.903
MazG
Nucleoside triphosphate hydrolase; Functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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