LepA protein (Mycobacterium xenopi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Mycobacterium xenopi

NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LepA	RplA	AWC32_22010	AWC32_17790	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	0.931
LepA	RpsI	AWC32_22010	AWC32_07660	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
LepA	rplM	AWC32_22010	AWC32_07665	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.958
LepA	rplO	AWC32_22010	AWC32_20380	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.929
LepA	rplS	AWC32_22010	AWC32_22465	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.944
LepA	rplT	AWC32_22010	AWC32_18145	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.944
LepA	rpmA	AWC32_22010	AWC32_22175	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family.	0.943
LepA	rpsB	AWC32_22010	AWC32_05035	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.	0.955
LepA	rpsD	AWC32_22010	AWC32_07725	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.937
LepA	rpsP	AWC32_22010	AWC32_08820	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family.	0.939
RplA	LepA	AWC32_17790	AWC32_22010	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	Back-translocating Elongation Factor EF4; binds to the ribosome on the universally-conserved alpha-sarcin loop; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.931
RplA	RpsI	AWC32_17790	AWC32_07660	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
RplA	rplM	AWC32_17790	AWC32_07665	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.996
RplA	rplO	AWC32_17790	AWC32_20380	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.998
RplA	rplS	AWC32_17790	AWC32_22465	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.997
RplA	rplT	AWC32_17790	AWC32_18145	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.996
RplA	rpmA	AWC32_17790	AWC32_22175	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family.	0.996
RplA	rpsB	AWC32_17790	AWC32_05035	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.	0.993
RplA	rpsD	AWC32_17790	AWC32_07725	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.996
RplA	rpsP	AWC32_17790	AWC32_08820	50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.	30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family.	0.995