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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MprBHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)    
Predicted Functional Partners:
mprA
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
ORX20792.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.939
PrrA_1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.883
regX3
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.880
ORX20002.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.879
PhoP
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.860
TrcR
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.859
MtrA
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.841
PrrA_2
ATPase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.798
kdpC
K+-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.795
Your Current Organism:
Mycobacterium xenopi
NCBI taxonomy Id: 1789
Other names: ATCC 19250, CCUG 28011, CCUG 31306, CIP 104035, DSM 43995, JCM 15661, M. xenopi, Mycobacterium xenopei, NCTC 10042
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