node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CoaBC | dut | AWC32_19210 | AWC32_23065 | Phosphopantothenate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.771 |
DnaN | ORX19392.1 | AWC32_17060 | AWC32_11120 | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
DnaN | dut | AWC32_17060 | AWC32_23065 | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.785 |
DnaN | thyA | AWC32_17060 | AWC32_13635 | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.803 |
LppK | ORX19392.1 | AWC32_12735 | AWC32_11120 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
LppK | dut | AWC32_12735 | AWC32_23065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.785 |
LppK | thyA | AWC32_12735 | AWC32_13635 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.803 |
ORX19392.1 | DnaN | AWC32_11120 | AWC32_17060 | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Binds the polymerase to DNA and acts as a sliding clamp; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
ORX19392.1 | LppK | AWC32_11120 | AWC32_12735 | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
ORX19392.1 | ORX21761.1 | AWC32_11120 | AWC32_22190 | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.917 |
ORX19392.1 | Tmk | AWC32_11120 | AWC32_12165 | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate kinase; Catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.948 |
ORX19392.1 | dut | AWC32_11120 | AWC32_23065 | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.805 |
ORX19392.1 | thyA | AWC32_11120 | AWC32_13635 | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.845 |
ORX21401.1 | dut | AWC32_23070 | AWC32_23065 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.789 |
ORX21761.1 | ORX19392.1 | AWC32_22190 | AWC32_11120 | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.917 |
ORX21761.1 | Tmk | AWC32_22190 | AWC32_12165 | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate kinase; Catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
ORX21761.1 | dcd | AWC32_22190 | AWC32_21060 | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | dCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.930 |
ORX21761.1 | dut | AWC32_22190 | AWC32_23065 | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.957 |
Tmk | ORX19392.1 | AWC32_12165 | AWC32_11120 | Thymidylate kinase; Catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator SirA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.948 |
Tmk | ORX21761.1 | AWC32_12165 | AWC32_22190 | Thymidylate kinase; Catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |