STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AmDm5_1663Thiamin-phosphate pyrophosphorylase. (197 aa)    
Predicted Functional Partners:
AmDm5_0876
Hydroxymethylpyrimidine phosphate kinase ThiD.
  
 
 0.955
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.864
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
  
 
 0.857
thiC
Hydroxymethylpyrimidine phosphate synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
 
 0.839
AmDm5_2600
Sulfur carrier protein ThiS.
  
 
 0.830
AmDm5_1664
Fructose-bisphosphate aldolase class I.
       0.722
AmDm5_2602
Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
     
  0.681
AmDm5_0240
Putative nucleic-acid-binding protein implicated in transcription termination; Ribosomal protein L7Ae family protein.
  
     0.642
AmDm5_2059
Sulfur carrier protein adenylyltransferase ThiF.
  
 
 0.619
AmDm5_1665
Hypothetical protein.
       0.613
Your Current Organism:
Acetobacter malorum
NCBI taxonomy Id: 178901
Other names: A. malorum, Acetobacter malorum Cleenwerck et al. 2002, DSM 14337, JCM 17274
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