node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AmDm5_2114 | AmDm5_2116 | AmDm5_2114 | AmDm5_2116 | GTP pyrophosphokinase, (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.761 |
AmDm5_2114 | AmDm5_2117 | AmDm5_2114 | AmDm5_2117 | GTP pyrophosphokinase, (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonuclease III; Digests double-stranded RNA. | 0.701 |
AmDm5_2114 | era | AmDm5_2114 | AmDm5_2118 | GTP pyrophosphokinase, (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.839 |
AmDm5_2114 | rpoK | AmDm5_2114 | AmDm5_2113 | GTP pyrophosphokinase, (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.837 |
AmDm5_2116 | AmDm5_2114 | AmDm5_2116 | AmDm5_2114 | Signal peptidase I; Belongs to the peptidase S26 family. | GTP pyrophosphokinase, (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.761 |
AmDm5_2116 | AmDm5_2117 | AmDm5_2116 | AmDm5_2117 | Signal peptidase I; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. | 0.915 |
AmDm5_2116 | AmDm5_2124 | AmDm5_2116 | AmDm5_2124 | Signal peptidase I; Belongs to the peptidase S26 family. | Membrane-associated zinc metalloprotease. | 0.681 |
AmDm5_2116 | atpE | AmDm5_2116 | AmDm5_0195 | Signal peptidase I; Belongs to the peptidase S26 family. | ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.743 |
AmDm5_2116 | era | AmDm5_2116 | AmDm5_2118 | Signal peptidase I; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.837 |
AmDm5_2116 | lepA | AmDm5_2116 | AmDm5_2102 | Signal peptidase I; Belongs to the peptidase S26 family. | Translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.723 |
AmDm5_2116 | rpoK | AmDm5_2116 | AmDm5_2113 | Signal peptidase I; Belongs to the peptidase S26 family. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.733 |
AmDm5_2116 | secD | AmDm5_2116 | AmDm5_2553 | Signal peptidase I; Belongs to the peptidase S26 family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.825 |
AmDm5_2116 | secF | AmDm5_2116 | AmDm5_2552 | Signal peptidase I; Belongs to the peptidase S26 family. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.772 |
AmDm5_2116 | yidC | AmDm5_2116 | AmDm5_2136 | Signal peptidase I; Belongs to the peptidase S26 family. | Inner membrane protein translocase component YidC, long form; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.703 |
AmDm5_2117 | AmDm5_2114 | AmDm5_2117 | AmDm5_2114 | Ribonuclease III; Digests double-stranded RNA. | GTP pyrophosphokinase, (p)ppGpp synthetase II; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.701 |
AmDm5_2117 | AmDm5_2116 | AmDm5_2117 | AmDm5_2116 | Ribonuclease III; Digests double-stranded RNA. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.915 |
AmDm5_2117 | era | AmDm5_2117 | AmDm5_2118 | Ribonuclease III; Digests double-stranded RNA. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.927 |
AmDm5_2117 | rpoK | AmDm5_2117 | AmDm5_2113 | Ribonuclease III; Digests double-stranded RNA. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.723 |
AmDm5_2117 | secD | AmDm5_2117 | AmDm5_2553 | Ribonuclease III; Digests double-stranded RNA. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.540 |
AmDm5_2117 | secF | AmDm5_2117 | AmDm5_2552 | Ribonuclease III; Digests double-stranded RNA. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.491 |