node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AmDm5_0796 | AmDm5_0797 | AmDm5_0796 | AmDm5_0797 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | 0.563 |
AmDm5_0796 | AmDm5_2954 | AmDm5_0796 | AmDm5_2954 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | Glutamate synthase [NADPH] large chain. | 0.567 |
AmDm5_0796 | AmDm5_3032 | AmDm5_0796 | AmDm5_3032 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | Acetolactate synthase large subunit. | 0.909 |
AmDm5_0796 | AmDm5_3033 | AmDm5_0796 | AmDm5_3033 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | Acetolactate synthase small subunit. | 0.992 |
AmDm5_0796 | ilvC | AmDm5_0796 | AmDm5_3034 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.979 |
AmDm5_0796 | ilvD | AmDm5_0796 | AmDm5_0215 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.640 |
AmDm5_0796 | leuA | AmDm5_0796 | AmDm5_0119 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.928 |
AmDm5_0796 | leuB | AmDm5_0796 | AmDm5_1141 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.918 |
AmDm5_0796 | leuD | AmDm5_0796 | AmDm5_1140 | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.454 |
AmDm5_0797 | AmDm5_0796 | AmDm5_0797 | AmDm5_0796 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | 0.563 |
AmDm5_0797 | AmDm5_2954 | AmDm5_0797 | AmDm5_2954 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | Glutamate synthase [NADPH] large chain. | 0.567 |
AmDm5_0797 | AmDm5_3033 | AmDm5_0797 | AmDm5_3033 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | Acetolactate synthase small subunit. | 0.976 |
AmDm5_0797 | ilvC | AmDm5_0797 | AmDm5_3034 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.944 |
AmDm5_0797 | ilvD | AmDm5_0797 | AmDm5_0215 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.704 |
AmDm5_0797 | leuA | AmDm5_0797 | AmDm5_0119 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.768 |
AmDm5_0797 | leuB | AmDm5_0797 | AmDm5_1141 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.695 |
AmDm5_0797 | leuC | AmDm5_0797 | AmDm5_1139 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.471 |
AmDm5_0797 | leuD | AmDm5_0797 | AmDm5_1140 | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.522 |
AmDm5_2954 | AmDm5_0796 | AmDm5_2954 | AmDm5_0796 | Glutamate synthase [NADPH] large chain. | Acetolactate synthase, catabolic; Belongs to the TPP enzyme family. | 0.567 |
AmDm5_2954 | AmDm5_0797 | AmDm5_2954 | AmDm5_0797 | Glutamate synthase [NADPH] large chain. | Benzoylformate decarboxylase; Belongs to the TPP enzyme family. | 0.567 |