node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GCA_001049355_03383 | metZ | GCA_001049355_03383 | GCA_001049355_03381 | Unannotated protein. | Unannotated protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.841 |
GCA_001049355_03383 | purT_1 | GCA_001049355_03383 | GCA_001049355_03384 | Unannotated protein. | Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | 0.799 |
metZ | GCA_001049355_03383 | GCA_001049355_03381 | GCA_001049355_03383 | Unannotated protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | Unannotated protein. | 0.841 |
metZ | purT_1 | GCA_001049355_03381 | GCA_001049355_03384 | Unannotated protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | 0.754 |
purC | purD | GCA_001049355_03746 | GCA_001049355_03757 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein; Belongs to the GARS family. | 0.998 |
purC | purE | GCA_001049355_03746 | GCA_001049355_00372 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.994 |
purC | purH | GCA_001049355_03746 | GCA_001049355_02941 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein. | 0.983 |
purC | purL | GCA_001049355_03746 | GCA_001049355_03728 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] | 0.969 |
purC | purM | GCA_001049355_03746 | GCA_001049355_03719 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein. | 0.978 |
purC | purN | GCA_001049355_03746 | GCA_001049355_02940 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.984 |
purC | purQ | GCA_001049355_03746 | GCA_001049355_03737 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] | 0.962 |
purC | purT_1 | GCA_001049355_03746 | GCA_001049355_03384 | Unannotated protein; Belongs to the SAICAR synthetase family. | Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | 0.822 |
purD | purC | GCA_001049355_03757 | GCA_001049355_03746 | Unannotated protein; Belongs to the GARS family. | Unannotated protein; Belongs to the SAICAR synthetase family. | 0.998 |
purD | purE | GCA_001049355_03757 | GCA_001049355_00372 | Unannotated protein; Belongs to the GARS family. | Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purD | purH | GCA_001049355_03757 | GCA_001049355_02941 | Unannotated protein; Belongs to the GARS family. | Unannotated protein. | 0.989 |
purD | purL | GCA_001049355_03757 | GCA_001049355_03728 | Unannotated protein; Belongs to the GARS family. | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] | 0.983 |
purD | purM | GCA_001049355_03757 | GCA_001049355_03719 | Unannotated protein; Belongs to the GARS family. | Unannotated protein. | 0.999 |
purD | purN | GCA_001049355_03757 | GCA_001049355_02940 | Unannotated protein; Belongs to the GARS family. | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | GCA_001049355_03757 | GCA_001049355_03737 | Unannotated protein; Belongs to the GARS family. | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] | 0.980 |
purD | purT_1 | GCA_001049355_03757 | GCA_001049355_03384 | Unannotated protein; Belongs to the GARS family. | Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. | 0.849 |