AFZ04650.1 protein (Oscillatoria nigroviridis)

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AFZ04650.1

DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (379 aa)

Predicted Functional Partners:

AFZ05275.1

0.999

polA

0.999

AFZ09596.1

0.997

dnaX

0.996

AFZ07332.1

0.990

AFZ08662.1

0.990

AFZ07330.1

0.989

dnaA

0.986

mutS

0.982

mutL

0.911

Your Current Organism:

Oscillatoria nigroviridis

NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFZ04650.1	AFZ05275.1	Osc7112_0002	Osc7112_0685	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	0.999
AFZ04650.1	AFZ07330.1	Osc7112_0002	Osc7112_2930	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR003141:IPR003587:IPR 004805:IPR006141; KEGG: cyc:PCC7424_3404 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; Hedgehog/intein hint, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha sub [...]	0.989
AFZ04650.1	AFZ07332.1	Osc7112_0002	Osc7112_2932	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	PFAM: OB-fold nucleic acid binding domain; TIGRFAM: intein C-terminal splicing region; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004365:IPR006141; KEGG: ter:Tery_1905 DNA polymerase III subunit alpha; PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: DNA polymerase III subunit alpha (Modular protein).	0.990
AFZ04650.1	AFZ08662.1	Osc7112_0002	Osc7112_4353	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Hypothetical protein; PFAM: ATP dependent DNA ligase domain; COGs: COG1793 ATP-dependent DNA ligase; KEGG: nar:Saro_1695 ATP dependent DNA ligase; SPTR: Putative uncharacterized protein.	0.990
AFZ04650.1	AFZ09596.1	Osc7112_0002	Osc7112_5358	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: cyj:Cyan7822_1292 DNA polymerase III subunit delta; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit.	0.997
AFZ04650.1	dnaA	Osc7112_0002	Osc7112_0001	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.	0.986
AFZ04650.1	dnaX	Osc7112_0002	Osc7112_5788	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.996
AFZ04650.1	mutL	Osc7112_0002	Osc7112_1328	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.911
AFZ04650.1	mutS	Osc7112_0002	Osc7112_4938	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.	0.982
AFZ04650.1	polA	Osc7112_0002	Osc7112_3862	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.999
AFZ05275.1	AFZ04650.1	Osc7112_0685	Osc7112_0002	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.999
AFZ05275.1	AFZ07330.1	Osc7112_0685	Osc7112_2930	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR003141:IPR003587:IPR 004805:IPR006141; KEGG: cyc:PCC7424_3404 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; Hedgehog/intein hint, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha sub [...]	0.986
AFZ05275.1	AFZ07332.1	Osc7112_0685	Osc7112_2932	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	PFAM: OB-fold nucleic acid binding domain; TIGRFAM: intein C-terminal splicing region; COGs: COG0587 DNA polymerase III alpha subunit; InterPro IPR004365:IPR006141; KEGG: ter:Tery_1905 DNA polymerase III subunit alpha; PFAM: Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: DNA polymerase III subunit alpha (Modular protein).	0.988
AFZ05275.1	AFZ08662.1	Osc7112_0685	Osc7112_4353	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	Hypothetical protein; PFAM: ATP dependent DNA ligase domain; COGs: COG1793 ATP-dependent DNA ligase; KEGG: nar:Saro_1695 ATP dependent DNA ligase; SPTR: Putative uncharacterized protein.	0.834
AFZ05275.1	AFZ09596.1	Osc7112_0685	Osc7112_5358	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: cyj:Cyan7822_1292 DNA polymerase III subunit delta; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit.	0.996
AFZ05275.1	dnaX	Osc7112_0685	Osc7112_5788	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.996
AFZ05275.1	mutL	Osc7112_0685	Osc7112_1328	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.	0.424
AFZ05275.1	polA	Osc7112_0685	Osc7112_3862	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.943
AFZ07330.1	AFZ04650.1	Osc7112_2930	Osc7112_0002	PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR003141:IPR003587:IPR 004805:IPR006141; KEGG: cyc:PCC7424_3404 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; Hedgehog/intein hint, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha sub [...]	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.989
AFZ07330.1	AFZ05275.1	Osc7112_2930	Osc7112_0685	PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: intein N-terminal splicing region; DNA-directed DNA polymerase III (polc); COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR003141:IPR003587:IPR 004805:IPR006141; KEGG: cyc:PCC7424_3404 DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; Hedgehog/intein hint, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha sub [...]	TIGRFAM: DNA polymerase III, delta' subunit; COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR004622; KEGG: ter:Tery_1565 DNA polymerase III subunit delta'; SPTR: DNA polymerase III subunit delta'; TIGRFAM: DNA polymerase III, delta prime subunit.	0.986

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