STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ04651.1PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594; KEGG: ava:Ava_3207 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Sensor protein. (486 aa)    
Predicted Functional Partners:
AFZ09796.1
Response regulator receiver modulated GAF sensor protein; PFAM: Response regulator receiver domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789:IPR003018; KEGG: ava:Ava_1423 response regulator receiver (CheY) and GAF domain-containing protein; PFAM: Signal transduction response regulator, receiver domain; GAF; SMART: Signal transduction response regulator, receiver domain; SPTR: Putative GAF sensor protein.
 
 
   0.790
AFZ08393.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: amr:AM1_3566 response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver.
 
   0.789
AFZ08759.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: amr:AM1_3566 response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver.
 
   0.788
AFZ10416.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ana:all2955 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver.
 
   0.788
AFZ05336.1
PFAM: Response regulator receiver domain; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; KEGG: naz:Aazo_2338 GAF sensor-containing adenylate/guanylate cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S).
  
 
   0.786
AFZ07763.1
Protein serine/threonine phosphatase with GAF(s) sensor(s); PFAM: Response regulator receiver domain; GAF domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001789:IPR003018:IPR010822:IPR001932; KEGG: ter:Tery_4817 response regulator receiver modulated serine phosphatase with GAF sensor; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction response regulator, receiver domain; GAF; SMART: Protein phosphatase 2C-like; Signal transduction response regulator, receiver domain; GAF; SPTR: Two-compone [...]
 
 
 
 0.763
AFZ07816.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ter:Tery_3155 adenylate/guanylate cyclase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor dom [...]
 
 
 0.414
AFZ06882.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cyt:cce_4659 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Two-component response regulator.
 
   0.400
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.