node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFZ05316.1 | AFZ05317.1 | Osc7112_0727 | Osc7112_0728 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | Uncharacterized protein family UPF0052; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.553 |
AFZ05316.1 | AFZ06361.1 | Osc7112_0727 | Osc7112_1877 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.646 |
AFZ05316.1 | AFZ06759.1 | Osc7112_0727 | Osc7112_2307 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: npu:Npun_R3855 SUA5/YciO/YrdC domain-containing protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Putative uncharacterized protein; Belongs to the SUA5 family. | 0.621 |
AFZ05316.1 | AFZ07032.1 | Osc7112_0727 | Osc7112_2617 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | Universal protein YeaZ; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ava:Ava_3835 peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ. | 0.960 |
AFZ05316.1 | AFZ10246.1 | Osc7112_0727 | Osc7112_6054 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | Translation factor SUA5; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388:IPR006070; KEGG: ter:Tery_0651 translation factor SUA5; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | 0.621 |
AFZ05316.1 | mnmA | Osc7112_0727 | Osc7112_4608 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.550 |
AFZ05316.1 | murB | Osc7112_0727 | Osc7112_4893 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.536 |
AFZ05316.1 | nnrD | Osc7112_0727 | Osc7112_4609 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.716 |
AFZ05316.1 | trmD | Osc7112_0727 | Osc7112_4719 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.621 |
AFZ05316.1 | tsaD | Osc7112_0727 | Osc7112_0986 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.911 |
AFZ05317.1 | AFZ05316.1 | Osc7112_0728 | Osc7112_0727 | Uncharacterized protein family UPF0052; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | 0.553 |
AFZ06361.1 | AFZ05316.1 | Osc7112_1877 | Osc7112_0727 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | 0.646 |
AFZ06361.1 | murB | Osc7112_1877 | Osc7112_4893 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.488 |
AFZ06759.1 | AFZ05316.1 | Osc7112_2307 | Osc7112_0727 | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: npu:Npun_R3855 SUA5/YciO/YrdC domain-containing protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Putative uncharacterized protein; Belongs to the SUA5 family. | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | 0.621 |
AFZ06759.1 | AFZ07032.1 | Osc7112_2307 | Osc7112_2617 | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: npu:Npun_R3855 SUA5/YciO/YrdC domain-containing protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Putative uncharacterized protein; Belongs to the SUA5 family. | Universal protein YeaZ; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ava:Ava_3835 peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ. | 0.621 |
AFZ06759.1 | tsaD | Osc7112_2307 | Osc7112_0986 | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: npu:Npun_R3855 SUA5/YciO/YrdC domain-containing protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Putative uncharacterized protein; Belongs to the SUA5 family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.717 |
AFZ07032.1 | AFZ05316.1 | Osc7112_2617 | Osc7112_0727 | Universal protein YeaZ; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ava:Ava_3835 peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ. | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: npu:Npun_F5352 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria. | 0.960 |
AFZ07032.1 | AFZ06759.1 | Osc7112_2617 | Osc7112_2307 | Universal protein YeaZ; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ava:Ava_3835 peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ. | PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: npu:Npun_R3855 SUA5/YciO/YrdC domain-containing protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Putative uncharacterized protein; Belongs to the SUA5 family. | 0.621 |
AFZ07032.1 | AFZ10246.1 | Osc7112_2617 | Osc7112_6054 | Universal protein YeaZ; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ava:Ava_3835 peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ. | Translation factor SUA5; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388:IPR006070; KEGG: ter:Tery_0651 translation factor SUA5; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC; Belongs to the SUA5 family. | 0.621 |
AFZ07032.1 | tsaD | Osc7112_2617 | Osc7112_0986 | Universal protein YeaZ; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905:IPR022496; KEGG: ava:Ava_3835 peptidase M22, glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Peptidase M22, glycoprotease; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.978 |