STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ05336.1PFAM: Response regulator receiver domain; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; KEGG: naz:Aazo_2338 GAF sensor-containing adenylate/guanylate cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S). (193 aa)    
Predicted Functional Partners:
AFZ07015.1
Multi-sensor signal transduction histidine kinase; PFAM: Cache domain; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003660:IPR013656:IPR003594:IPR000014:IPR 001610; KEGG: npu:Npun_AR133 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; PAS fold-4; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; PAS; PAC moti [...]
 
 
 0.825
AFZ08706.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR001610:IPR003661:IPR 003594:IPR008207:IPR013655:IPR013767; KEGG: syp:SYNPCC7002_A1261 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; Signal transduction response regulator, receiver domain [...]
   
 
 0.821
AFZ08767.1
Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR001789:IPR001610:IPR003018:IPR 003661:IPR003594:IPR013655:IPR013656; KEGG: npu:Npun_F2854 GAF sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; GAF; PAS fold-4; PAS fold-3; Signal transduction response [...]
 
 
 0.821
AFZ08814.1
Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR013655:IPR013656; KEGG: npu:Npun_F1203 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; PAS fold-4; SMART: ATPase-like, ATP-binding domain; GAF; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimeris [...]
 
 
 0.814
AFZ07700.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013656:IPR013767:IPR013655:IPR003661:IPR 003594:IPR000014:IPR001610; KEGG: npu:Npun_R3263 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold-4; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor [...]
 
 
 
 0.813
AFZ08309.1
Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003660:IPR003661:IPR003594; KEGG: ana:alr1551 two-component sensor histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transdu [...]
 
 
 0.813
AFZ06718.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR001789:IPR013655:IPR003018:IPR 003594:IPR001610; KEGG: npu:Npun_R3581 PAS/PAC sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; PAS fold-3; GAF; ATPase-like, ATP-binding domain; [...]
 
 
 0.812
AFZ08758.1
PFAM: CBS domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000644:IPR003594; KEGG: amr:AM1_3565 serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF and PAS/PAC sensor; PFAM: ATPase-like, ATP-binding domain; Cystathionine beta-synthase, core; SMART: ATPase-like, ATP-binding domain; Cystathionine beta-synthase, core; SPTR: Sensor protein (Modular protein).
 
 
 
 0.812
AFZ07848.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013656:IPR013767:IPR003018:IPR013655:IPR 003594:IPR000014:IPR001610:IPR003661; KEGG: npu:Npun_R3263 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; PAS fold-4; PAS fold; GAF; SMART: ATPase-like, ATP-binding domain; Signal transduction his [...]
 
 
 0.807
AFZ08882.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003018:IPR013656:IPR013655:IPR013767:IPR 003661:IPR003594:IPR000014:IPR001610; KEGG: npu:Npun_F1203 multi-sensor signal transduction histidine kinase; PFAM: GAF; PAS fold-4; PAS fold-3; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; [...]
 
 
 0.805
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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