STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
AFZ05695.1PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CheR methyltransferase, SAM binding domain; His Kinase A (phosphoacceptor) domain; PAS fold; COGs: COG0642 Signal transduction histidine kinase; InterProIPR022642:IPR013656:IPR003661:IPR003594:IPR 000014; KEGG: ana:all1716 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-4; MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; SMART: [...] (803 aa)    
Predicted Functional Partners:
AFZ05697.1
MCP methyltransferase/methylesterase, CheR/CheB; PFAM: CheB methylesterase; CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000673:IPR022641:IPR022642:IPR000780; KEGG: ava:Ava_0314 signal transduction histidine kinase (STHK) with CheB and CheR activity; PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; PR [...]
  
 0.979
AFZ06388.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR001789; KEGG: amr:AM1_5077 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; CheW-like protein [...]
  
 0.950
AFZ06387.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: cyj:Cyan7822_4348 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein signaling domain.
 
 
 
 0.911
AFZ06385.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: cyj:Cyan7822_4352 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Putative CheW protein.
  
 
 0.910
AFZ05544.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
0.803
AFZ09706.1
PFAM: CheB methylesterase; COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: ana:all1847 hypothetical protein; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: Putative uncharacterized protein.
  
 0.634
AFZ09704.1
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789; KEGG: ava:Ava_4696 GAF sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bindin [...]
 
 
0.627
AFZ06595.1
PFAM: Universal stress protein family; Osmosensitive K+ channel His kinase sensor domain; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR003852:IPR006016; KEGG: npu:Npun_R0299 osmosensitive K+ channel histidine kinase sensor subunit; PFAM: Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal; UspA; SPTR: Potassium-dependent ATPase subunit D'.
 
  
   0.622
AFZ10185.1
PFAM: Histidine kinase; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG4585 Signal transduction histidine kinase; InterPro IPR001789:IPR011712:IPR003594; KEGG: npu:Npun_F1799 response regulator receiver sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver sens [...]
 
 
 0.585
AFZ08652.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: cyn:Cyan7425_0748 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein.
 
 
   0.582
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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