STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ05858.1RNA-directed DNA polymerase; PFAM: HNH endonuclease; Reverse transcriptase (RNA-dependent DNA polymerase); Group II intron, maturase-specific domain; COGs: COG3344 Retron-type reverse transcriptase; InterPro IPR000477:IPR013597:IPR002711; KEGG: ter:Tery_4731 RNA-directed DNA polymerase (reverse transcriptase); PFAM: Reverse transcriptase; Group II intron, maturase-specific; HNH endonuclease; SPTR: Putative uncharacterized protein. (566 aa)    
Predicted Functional Partners:
AFZ05859.1
Transposase, IS605 OrfB family; PFAM: Putative transposase DNA-binding domain; Probable transposase; TIGRFAM: transposase, IS605 OrfB family, central region; COGs: COG0675 Transposase and inactivated derivatives; InterPro IPR010095:IPR001959; KEGG: ana:all5207 transposase; PFAM: Transposase, probable, IS891/IS1136/IS1341; Transposase, IS605 OrfB, C-terminal; SPTR: Transposase; TIGRFAM: Transposase, IS605 OrfB, C-terminal.
       0.773
cas1
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
      0.419
AFZ05857.1
KEGG: sli:Slin_0031 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.417
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.