STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AFZ05881.1PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410:IPR014043:IPR020801; KEGG: cyn:Cyan7425_3992 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Acyl-carrier-protein S-malonyltransferase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase. (293 aa)    
Predicted Functional Partners:
AFZ05856.1
PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR020841; KEGG: ter:Tery_0510 3-oxoacyl-(acyl carrier protein) synthase II; PFAM: Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase I; SMART: Polyketide synthase, beta-ketoacyl synthase domain; SPTR: 3-oxoacyl-(Acyl carrier protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 0.999
fabH
3-oxoacyl-(acyl-carrier-protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.999
AFZ06678.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.999
AFZ09660.1
Enoyl-(acyl-carrier-protein) reductase (NADH); PFAM: short chain dehydrogenase; COGs: COG0623 Enoyl-(acyl-carrier-protein); InterPro IPR002198; KEGG: npu:Npun_R5510 enoyl-(acyl carrier protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: Enoyl-[acyl-carrier-protein] reductase (NADH); SPTR: Enoyl-(Acyl carrier protein) reductase.
 
 
 0.992
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 
 0.989
AFZ09433.1
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR001242:IPR000873:IPR006163:IPR 020806; KEGG: cyc:PCC7424_5753 amino acid adenylation domain protein; PFAM: AMP-dependent synthetase/ligase; Condensation domain; Phosphopantetheine-binding; PRIAM: Phenylalanine racemase (ATP-hydrolyzing); SMART: Polyketide synthase, phosphopantetheine-binding; SPTR: Amino acid adenylation domain pro [...]
 
 0.988
AFZ09280.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 0.987
AFZ09437.1
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR020806:IPR001242:IPR000873:IPR 006163; KEGG: npu:Npun_R3026 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase/ligase; Condensation domain; Phosphopantetheine-binding; PRIAM: Aspartate racemase; SMART: Polyketide synthase, phosphopantetheine-binding; SPTR: Amino acid adenylation domain protein; TIGRFAM [...]
 
 0.987
AFZ09430.1
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; Male sterility protein; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; thioester reductase domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR010080:IPR001242:IPR000873:IPR 006163:IPR013120:IPR020806; KEGG: npu:Npun_R3433 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase/ligase; Condensation domain; Phosphopantetheine-binding; Male sterility, NAD-binding; SMART: Polyketide synthase, phosph [...]
 
 0.981
AFZ09439.1
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; Nonribosomal peptide synthase; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR020806:IPR000873:IPR006163:IPR 001242:IPR013624; KEGG: nde:NIDE1742 putative multi-domain non-ribosomal peptide synthetase; PFAM: Condensation domain; AMP-dependent synthetase/ligase; Phosphopantetheine-binding; Non-ribosomal peptide synthetase; PRIAM: Long-chain-fatty-acid--[acyl-carrier-protein] lig [...]
 
 0.979
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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