STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ06231.1Hypothetical protein; PFAM: NAD synthase; TIGRFAM: TIGR00268 family protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR018317; KEGG: cyn:Cyan7425_3314 hypothetical protein; PFAM: Queuosine synthesis; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00268. (275 aa)    
Predicted Functional Partners:
AFZ10245.1
PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein; COGs: COG1641 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0272; InterPro IPR002822; KEGG: ter:Tery_0652 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0272; Belongs to the LarC family.
 
 0.989
AFZ09011.1
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; PFAM: AIR carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: ter:Tery_4722 putative phosphoribosylaminoimidazole carboxylase catalytic subunit; PFAM: Phosphoribosylaminoimidazole carboxylase, core; SPTR: Putative phosphoribosylaminoimidazole carboxylase catalytic subunit.
  
 0.979
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
    
 0.740
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
    0.706
AFZ04721.1
Cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: npu:Npun_F6157 cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein.
 
    0.613
AFZ05517.1
Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
      0.577
AFZ07391.1
NADP-dependent oxidoreductase domain protein; PFAM: Aldo/keto reductase family; COGs: COG1453 oxidoreductase of the aldo/keto reductase family; InterPro IPR023210; KEGG: npu:Npun_F0061 aldo/keto reductase; PFAM: NADP-dependent oxidoreductase domain; SPTR: Aldo/keto reductase.
 
    0.560
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.557
AFZ05226.1
NADP-dependent oxidoreductase domain protein; PFAM: Aldo/keto reductase family; COGs: COG1453 oxidoreductase of the aldo/keto reductase family; InterPro IPR023210; KEGG: npu:Npun_R5496 aldo/keto reductase; PFAM: NADP-dependent oxidoreductase domain; SPTR: Aldo/keto reductase.
 
    0.534
AFZ06230.1
PFAM: Protein of unknown function (DUF820); InterPro IPR008538; KEGG: mar:MAE_11000 hypothetical protein; PFAM: Domain of unknown function DUF820; SPTR: Putative uncharacterized protein.
       0.486
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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