STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AFZ06454.1Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR000160:IPR001789:IPR013767:IPR 001633:IPR001610; KEGG: cyj:Cyan7822_2526 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylat [...] (726 aa)    
Predicted Functional Partners:
AFZ08706.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR001610:IPR003661:IPR 003594:IPR008207:IPR013655:IPR013767; KEGG: syp:SYNPCC7002_A1261 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; Signal transduction response regulator, receiver domain [...]
 
 
0.986
AFZ05106.1
Multi-sensor hybrid histidine kinase; PFAM: GAF domain; HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CHASE4 domain; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR007892:IPR003660:IPR013655:IPR 003018:IPR003661:IPR003594:IPR001789:IPR008207:IPR001610; KEGG: ter:Tery_0943 multi-sensor hybrid histidine kinase; PFAM: CHASE4; HAMP linker domain; PAS fold-3; GAF; Signal transduction histidine kinase, subgroup 1, dimeri [...]
 
 
 0.985
AFZ05847.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003660:IPR003018:IPR013655:IPR 013656:IPR003661:IPR003594:IPR001789:IPR008207:IPR001610; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; HAMP linker domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domai [...]
  
 
 0.985
AFZ08604.1
Multi-sensor hybrid histidine kinase; PFAM: CBS domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR000644:IPR001610:IPR003018:IPR 003661:IPR003594:IPR001789:IPR013655:IPR013767:IPR008207; KEGG: ter:Tery_4447 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domai [...]
  
 
0.985
AFZ09225.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR013655:IPR013767:IPR 003018:IPR003661:IPR003594:IPR001789:IPR008207:IPR001610; KEGG: cya:CYA_2836 sensory box histidine kinase/response regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-4; PAS fold-3; PAS fold [...]
 
 
0.985
AFZ09704.1
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789; KEGG: ava:Ava_4696 GAF sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bindin [...]
  
 
0.973
AFZ05544.1
Signal transduction histidine kinase with CheB and CheR activity; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.936
AFZ09371.1
Adenylate/guanylate cyclase with GAF and PAS/PAC sensors; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR003018:IPR013656:IPR001054; KEGG: ana:alr1966 two-component sensor histidine kinase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; PAS fold-4; PRIAM: Guanylate cyclase; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; PAS; GAF; SPTR: PAS fold family; TIGRFAM: PAS; Belongs to the adenylyl cyclase class-4/guanylyl cyc [...]
 
 
 0.935
AFZ09707.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR001610:IPR003661:IPR 003594:IPR013656; KEGG: npu:Npun_F3541 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; [...]
  
 
0.915
AFZ09323.1
Multi-sensor signal transduction histidine kinase; PFAM: HAMP domain; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR004010:IPR003660:IPR013767:IPR 013655:IPR003661:IPR003594:IPR001610; KEGG: dba:Dbac_3479 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; HAMP linker domain; Cache; PAS fold; [...]
 
 
 0.910
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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