STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (343 aa)    
Predicted Functional Partners:
fcl
GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.991
AFZ08527.1
PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: ter:Tery_1856 mannose-1-phosphate guanylyltransferase (GDP); PFAM: Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase (GDP).
 
 
 0.939
AFZ07904.1
Mannose-1-phosphate guanylyltransferase, Phosphoglucosamine mutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835:IPR001451:IPR005844; KEGG: npu:N [...]
    
 0.938
cugP
Mannose-1-phosphate guanylyltransferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate.
    
 0.909
gmd-2
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 
0.905
AFZ06429.1
PFAM: Thioredoxin; TIGRFAM: thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR005746:IPR013766; KEGG: ava:Ava_2654 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; Belongs to the thioredoxin family.
    
   0.706
AFZ05800.1
PFAM: EAL domain; Polysaccharide biosynthesis protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869:IPR001633; KEGG: npu:Npun_F1367 polysaccharide biosynthesis protein CapD; PFAM: Polysaccharide biosynthesis protein CapD-like; Diguanylate phosphodiesterase, EAL domain; SMART: Diguanylate phosphodiesterase, EAL domain; SPTR: Polysaccharide biosynthesis protein CapD.
  
  
 0.580
AFZ06862.1
NAD-dependent epimerase/dehydratase; PFAM: Polysaccharide biosynthesis protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR001509; KEGG: amr:AM1_3626 capsular polysaccharide biosynthesis protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative uncharacterized protein.
  
  
 0.561
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
   0.521
AFZ05792.1
Undecaprenyl-phosphate galactose phosphotransferase; PFAM: Bacterial sugar transferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: npu:Npun_F2447 sugar transferase; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Sugar transferase.
  
  
 0.488
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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