STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ06928.1Heat shock protein DnaJ domain protein; PFAM: DnaJ C terminal region; DnaJ domain; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939; KEGG: ter:Tery_4397 heat shock protein DnaJ-like; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ-like. (336 aa)    
Predicted Functional Partners:
AFZ09439.1
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; Nonribosomal peptide synthase; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR020806:IPR000873:IPR006163:IPR 001242:IPR013624; KEGG: nde:NIDE1742 putative multi-domain non-ribosomal peptide synthetase; PFAM: Condensation domain; AMP-dependent synthetase/ligase; Phosphopantetheine-binding; Non-ribosomal peptide synthetase; PRIAM: Long-chain-fatty-acid--[acyl-carrier-protein] lig [...]
   
 
 0.929
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.924
dnaK-3
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.922
dnaK-2
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.918
AFZ10119.1
PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: tjr:TherJR_2450 chaperone protein DnaK; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK.
 
 0.890
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.876
AFZ08057.1
PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: ava:Ava_0572 heat shock protein HSP70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70.
  
 0.875
AFZ05962.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: cyj:Cyan7822_3471 NADH dehydrogenase; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (qui [...]
    
   0.862
AFZ08169.1
PFAM: MreB/Mbl protein; Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: cyn:Cyan7425_4102 heat shock protein 70; PFAM: Heat shock protein 70; SPTR: DnaK family protein.
  
 0.809
AFZ08319.1
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
  
 0.768
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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