STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ07209.1PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: gwc:GWCH70_3145 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Aldehyde Dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.943
AFZ09625.1
PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR015590:IPR001670; KEGG: cyc:PCC7424_3674 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase domain; PRIAM: Acetaldehyde dehydrogenase (acetylating); SPTR: Alcohol dehydrogenase, iron-containing family; alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.931
AFZ08249.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COGs: COG1062 Zn-dependent alcohol dehydrogenase class III; InterPro IPR020843:IPR013154:IPR013149:IPR014183; KEGG: amr:AM1_2463 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; SMART: Polyketide synthase, enoylreductase; SPTR: Zinc-binding alcohol dehydrogenase; TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alc [...]
 
 0.923
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.921
AFZ06192.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1064 Zn-dependent alcohol dehydrogenase; InterPro IPR020843:IPR013154:IPR013149; KEGG: npu:Npun_R0575 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; PRIAM: Mannitol dehydrogenase; SMART: Polyketide synthase, enoylreductase; SPTR: Alcohol dehydrogenase GroES domain protein.
  
 
 0.915
AFZ09681.1
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: npu:Npun_F0840 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase domain; SPTR: Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.911
AFZ07803.1
PFAM: Acylphosphatase; COGs: COG1254 Acylphosphatase; HAMAP: Acylphosphatase; InterPro IPR001792; KEGG: npu:Npun_F1030 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase.
    
 0.906
AFZ07208.1
PFAM: Protein of unknown function (DUF779); COGs: COG3564 conserved hypothetical protein; InterPro IPR008497; KEGG: gct:GC56T3_3212 protein of unknown function DUF779; PFAM: Protein of unknown function DUF779; SPTR: Putative uncharacterized protein.
 
    0.882
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.591
AFZ08231.1
Putative phenylacetate-CoA ligase; COGs: COG1541 Coenzyme F390 synthetase; KEGG: npu:Npun_R1251 putative phenylacetate-CoA ligase; SPTR: Putative phenylacetate-CoA ligase.
   
 
 0.529
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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